Technical Proceedings of the 2010 NSTI Nanotechnology Conference & Expo - Nanotech 2010
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Nanotech 2010 Vol. 3
Chapter 3: Nano for Biotech, Interfaces & Tissues
Size of the Pores Created by an Electric Pulse: Microsecond vs Millisecond Pulses
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| Authors: | G. Saulis, R. Saule |
| Affiliation: | Vytautas Magnus University, LT |
| Pages: | 226 - 229 |
| Keywords: | electroporation, pore size, bleomycin, eryhtrocytes, mouse hepatoma cells, CHO |
| Abstract: | Modeling studies have revealed that the pulse of nanosecond-duration should create smaller pores than the pulse of micro-millisecond duration. It can be expected, that similar differences should also exist between the pore populations created by the pulses of micro- and millisecond-durations. Here, we compared the size of the pores created by a square-wave electric pulse with the duration of 100 us and 2 ms. For the cells studied, short 100 us-duration pulse created smaller pores than longer 2 ms-duration pulse |
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